Publications

Doctoral Thesis

  • Title: In-silico studies of microRNAs regulation in higher eukaryotes from the perspective of molecular evolution.
    Topics: Bioinformatics, Molecular Evolution, MicroRNAs, Human Diseases, Epigenetics.
    Supervisor: Prof. T.C. Ghosh
    Workplace: Bose Institute (J.C. Bose Institute), Kolkata, India
    University: Maulana Abul Kalam Azad University of Technology, West Bengal, India
    Year: 2017

2026

  • Longo M, Desiderio A, Masulli M, Das J, Spinelli R, Parrillo L, Rotondo M, Zatterale F, Volpe M, Riccardi G, Vaccaro O, Miele C, Napoli R, Beguinot F, Raciti GA. Blood-Based DNA Methylation Models Improve Short-term Cardiovascular Risk Stratification in Individuals With Type 2 Diabetes. Diabetes Care, 49(9):1705–1713.

2025

  • Govender M, Das J, Hopkins FR, Svanberg C, Nordgren J, Hagbom M, Klingström J, Nilsdotter-Augustinsson Å, Yong YK, Velu V, Raju S, Sjöwall J, Shankar EM, Nyström S, Larsson M. Altered DNA Methylation Pattern Contributes to Differential Epigenetic Immune Signaling in the Upper Respiratory Airway of Unvaccinated COVID-19 Patients. Cells, 14(21):1673.
  • Das J. TwistMethNext: An end-to-end Nextflow-based bioinformatics pipeline for Twist NGS DNA methylation data analysis. protocols.io.

2024

  • Shahin H, Belcastro L, Das J, et al. MicroRNA‐155 mediates multiple gene regulations pertinent to human adipose-derived mesenchymal stem cells in skin regeneration. Front. Bioeng. Biotechnol. 12:1328504.
  • Volpe, M., Miralto, M., & Das, J. methylRv2: An EPICv2 user interface solution to DNA methylation array data analysis. 2024
  • Volpe, M., Miralto, M., & Das, J. TranscriptR: GUI for transcriptome data analysis. 2024

2023

  • Volpe, M., & Das, J. methylR: a graphical interface for comprehensive DNA methylation array data analysis. Bioinformatics, 39(4), btad184.
  • Braian, C., Karlsson, L., Das, J., & Lerm, M. Selected β-Glucans Act as Immune-Training Agents by Improving Anti-Mycobacterial Activity in Human Macrophages: A Pilot Study. J Innate Immun 15(1):751–764.
  • Lundquist, H., Andersson, H., Chew, M. S., Das, J., Turkina, M. V., & Welin, A. The Olfactomedin-4-Defined Human Neutrophil Subsets Differ in Proteomic Profile in Healthy Individuals and Patients with Septic Shock. J Innate Immun 15(1):351–364.
  • Lundquist, H., Andersson, H., Chew, M. S., Das, J., Turkina, M. V., & Welin, A. miRNome and Proteome Profiling of Human Keratinocytes and Adipose Derived Stem Cells Proposed miRNA-Mediated Regulations of Epidermal Growth Factor and Interleukin 1-Alpha. Int. J. Mol. Sci. 24(5), 4956.
  • Verma, D., Kasic, N.‐K., Jeppsson, F., Eding, C. B., Lysiak, M., Fekri, S. Z., Das, J., & Enerback, C. Differential DNA Methylation of MicroRNA-Encoding Genes in Psoriatic Epidermis Highlights the Wnt Pathway. Journal of Investigative Dermatology, 143(5), S140.
  • Shahin, H., Abdallah, S., Das, J., et al. Mirmome and proteome profiling of human keratinocytes and adipose-derived stem cells... J Plast, Reconstructive & Aesthetic Surgery, 87:S18–S19, 2023.
  • Verma, D., Kasic, N., et al. Altered methylation of microRNA in the psoriatic epidermis highlights the Wnt pathway. Journal of Investigative Dermatology, 143(5), S140, 2023.

2022

  • Pehrson I, Sayyab S, Das J, Idh N, Paues J, Méndez-Aranda M, Ugarte-Gil C, Lerm M. The spectrum of tuberculosis described as differential DNA methylation patterns in alveolar macrophages and alveolar T cells. Clinical Epigenetics, 14(1):1–12.
  • Das J, Idh N, Sikkeland LI, Paues J, Lerm M. DNA methylome-based validation of induced sputum as an effective protocol to study lung immunity: construction of a classifier of pulmonary cell types. Epigenetics, 17(8):882-93.
  • Huoman J, Sayyab S, Apostolou E, Karlsson L, Porcile L, Rizwan M, Sharma S, Das J, Rosén A, Lerm M. Epigenetic rewiring of pathways related to odour perception in immune cells exposed to SARS-CoV-2 in vivo and in vitro. Epigenetics.
  • Łysiak M, Das J, Malmström A, Söderkvist P. Methylation associated with long- or short-term survival in glioblastoma patients from the Nordic phase 3 trial. Front Genet. 13:934519.
  • Lundquist H, Andersson H, et al. The Olfm4-defined human neutrophil subsets differ in proteomic profile in septic shock. bioRxiv 2022.
  • Verma, D., Kasic, N., et al. Differential DNA Methylation of microRNA-encoding Genes in Psoriatic Epidermis Highlights the Wnt Pathway. Journal of Investigative Dermatology, 142(12), S229, 2022.
  • Lysiak, M., Das, J., et al. Methylome analysis of short versus long‐term GBM survivors... Brain Tumor Res Treat, 10(Suppl), 2022.
  • Lerm, M., & Das, J. Biomarker for detection of mycobacterial exposure and infection. WO2022169394A1, 2022.
  • Lerm, M., Das, J., & Sayyab, S. Method for determining SARS-CoV-2 exposure with or without remaining symptoms. WO2022119495A1, 2022.

2021

  • Karlsson L, Das J, Nilsson M, et al. A differential DNA methylome signature of pulmonary immune cells from individuals converting to latent tuberculosis infection. Scientific Reports, 11(1):1-3.
  • Kalsum S, Andersson B, Das J, Schön T, Lerm M. A high-throughput screening assay based on automated microscopy for monitoring antibiotic susceptibility of Mycobacterium tuberculosis phenotypes. BMC Microbiology. 21(1):1-4.
  • Zhu GH, Azharuddin M, Islam R, Rahmoune H, Deb S, Kanji U, Das J, et al. Innate Immune Invisible Ultrasmall Gold Nanoparticles—Framework for Synthesis and Evaluation. ACS Applied Materials & Interfaces. 13(20):23410-22.
  • Singhania A, Dubelko P, Kuan R, Chronister WD, Muskat K, Das J, et al. CD4+ CCR6+ T cells dominate the BCG-induced transcriptional signature. EBioMedicine. 74:103746.
  • Das J, Idh N, Paues J, Lerm M. A DNA methylome biosignature in alveolar macrophages from TB-exposed individuals predicts exposure to mycobacteria. medRxiv 2021.
  • Pehrson I, Das J, et al. DNA methylomes derived from alveolar macrophages display distinct patterns in latent tuberculosis. MedRxiv 2021.
  • Huoman J, Sayyab S, et al. Mild SARS-CoV-2 infection modifies DNA methylation of PBMCs from COVID-19 convalescents. medRxiv 2021.
  • Pehrson I, Braian C, et al. DNA methylation profiling of immune cells from tuberculosis-exposed individuals overlaps with BCG-induced epigenetic changes... medRxiv 2021.

2019

  • Das J, Verma D, Gustafsson M, Lerm M. Identification of DNA methylation patterns predisposing for an efficient response to BCG vaccination in healthy BCG-naïve subjects. Epigenetics. 14(6):589-601.

2018

  • Sen K, Bhattacharyya D, Sarkar A, Das J, et al. Exploring the major cross-talking edges of competitive endogenous RNA networks in human Chronic and Acute Myeloid Leukemia. Biochimica et Biophysica Acta (BBA)-General Subjects. 1862(9):1883-92.

2014

2013

  • Das, J., Chakraborty, S., Podder, S., Ghosh, T.C. Complex-forming proteins escape the robust regulations of miRNA in human. FEBS letters 587, 2284–2287.

2011

  • Gupta, S., Kumari, K., Das, J., Lata, C., Puranik, S., & Prasad, M. Development and utilization of novel intron length polymorphic markers in foxtail millet (Setaria italica (L.) P. Beauv.). Genome, 54(7), 586-602.